Reinterpretation of the genetics of susceptibility of Aedes aegypti to Plasmodium gallinaceum
Autor(es): Thathy V,Severson D W,Christensen B M
Resumo: Several studies have demonstrated a genetic basis for variation in susceptibility of Aedes aegypti to Plasmodium gallinaceum. Although 25 yr ago it was reported that P. gallinaceum susceptibility in Ae. aegypti is determined primarily by a single autosomal dominant gene, evidence for additional genetic factors has emerged. Two sublines, 1 refractory and 1 of intermediate susceptibility to P. gallinaceum, have been selected from the Moyo-In-Dry strain (MOYO) of Ae. aegypti. Prior to selection, the MOYO population was 20.3% refractory. Genetic crosses of the highly susceptible Rockefeller strain (ROCK) and the 2 selected sublines of the MOYO strain provide evidence for a complex mode of inheritance of Plasmodium susceptibility in Ae. aegypti.
Imprenta: The Journal of parasitology, v. 80, n. 5, p. 705-712, 1994
Identificador do objeto digital: 10.2307/3283249
Descritores: Aedes aegypti - Pathogenesis ; Aedes aegypti - Immunology
Data de publicação: 1994