Autor(es): Mellink J J

Resumo: Mice repeatedly exposed to uninfective bites or injected with noninfectious salivary gland homogenates from Aedes aegypti produced low levels of antibodies neutralizing Venezuelan equine encephalomyelitis (VEE) virus of mosquito origin. Effects on subsequent mosquito-borne infections could not be demonstrated, probably because the antivirus titers were too low. Cutaneous (type III-like) hypersensitivity reactions of mice to bites did not significantly affect the concurrent transmission of VEE virus. Preexisting edema and/or recent inflammation at the site of infective bites considerably reduced infection rates of mice exposed to infected mosquitoes.

Imprenta: Journal of Medical Entomology, v. 19, n. 4, p. 371-375, 1982

Identificador do objeto digital: 10.1093/jmedent/19.4.371

Descritores: Aedes aegypti - Pathogenesis ; Aedes aegypti - Proteins ; Aedes aegypti - Antibodies ; Aedes aegypti - Inflammation ; Aedes aegypti - Viral infections ; Aedes aegypti - virus ; Aedes aegypti - Transmission ; Aedes aegypti - Immunology ; Aedes aegypti - Public health

Data de publicação: 1982