Studies with Brugia pahangi 10. An attempt to demonstrate the sharing of antigenic determinants between the worm and its hosts
Autor(es): McGreevy P B,Ismail M M,Phillips T M,Denham D A
Resumo: Infective stage Brugia pahangi that were reared in Aedes aegypti survived equally well in cats that had previously been immunized against mosquito tissue and in a normal cat. The survival of third, fourth, juvenile, adult and microfilarial stages of B. pahangi that were recovered from cats was similar in jirds that had been immunized against cat antigens and in normal jirds. Host antigenic determinants were not detected on the surface of larvae in substantial amounts using fluorescent antibody techniques. It is unlikely that B. pahangi evades the immune response of its vertebrate hosts by masquerading as self" behind host antigens."
Imprenta: Journal of Helminthology, v. 49, n. 2, p. 107-113, 1975
Identificador do objeto digital: 10.1017/S0022149X00023221
Descritores: Aedes aegypti - Immune response ; Aedes aegypti - Pathogenesis ; Aedes aegypti - Proteins ; Aedes aegypti - Antibodies ; Aedes aegypti - Immune response ; Aedes aegypti - Immunology
Data de publicação: 1975
