Stage-specific expression of two actin genes in the yellow fever mosquito, Aedes aegypti
Autor(es): Vyazunova I,Lan Q
Resumo: Abstract The expression patterns of two muscle-specific actin genes were studied in the yellow fever mosquito, Aedes aegypti. The coding sequence of AeAct-2 exhibits between 82 and 85% similarity with coding sequences of the Drosophila melanogaster and predicted Anopheles gambiae actin genes. The transcription of the AeAct-2 gene was differentially regulated during developmental stages with higher levels of expression in larvae and lower levels in pupae and adults. The AeAct-2 gene is mainly expressed in the head and body wall tissues. Transcripts of the AeAct-3 gene are not detectable in larvae until late 4th instar and the level increased in male pupae and early male adults. The main site of expression of the AeAct-3 gene was the thoracic tissue. Thus, AeAct-3 is the first reported male-specific actin gene in mosquitoes.
Palavras-Chave: Actin; Mosquito; Gene expression; Sex-specific gene; Muscle
Imprenta: Insect Molecular Biology, v. 13, n. 3, p. 241-249, 2004
Identificador do objeto digital: 10.1111/j.0962-1075.2004.00481.x
Descritores: Aedes aegypti - DNA ; Aedes aegypti - Molecular Structure ; Aedes aegypti - Pathogenesis ; Aedes aegypti - Proteins ; Aedes aegypti - Public health
Data de publicação: 2004
