Vector population manipulation for control of arboviruses - a novel prospect for India
Autor(es): Niranjan Reddy Bp, Gupta Bhavna, Rao B Prasad
Resumo: India, the seventh largest country in the world, has diverse geographical - climatic regions with vast rural - peri-urban areas. Many are experiencing an escalation in the spread - intensity of numerous human diseases transmitted by insects. Classically, the management of these vector-borne diseases is underpinned by either chemical insecticides -/or environmental management targeted at the vector. However, these methods or their present implementation do not offer acceptable levels of control, - more effective - sustainable options are now available. Genetic strategies for the prevention of arbovirus transmission are most advanced for dengue - chikungunya, targeting their primary vector, Aedes aegypti. The national burden in terms of morbidity - mortality as a direct consequence of dengue virus in India is considered to be the largest worldwide, over 4 times that of any other country. Presently, new genetic technologies are undergoing field evaluation of their biosafety - efficacy in several countries. This paper discusses the merits of these approaches - argues for fair - transparent appraisal in India as a matter of urgency. Identification of any associated risks - their appropriate mitigation are fundamental to that process.
Palavras-Chave: India; Arbovirus; Chikungunya; Dengue; Genetic control; Genetically modified; Public health
Imprenta: Pest Management Science, v. 70, n. 4, p. 517-523, 2014
Identificador do objeto digital: 10.1002/ps.3676
Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Genome ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Public health
Data de publicação: 2014
