Update on rheumatic manifestations of infectious diseases
Autor(es): Becker Jennifer, Winthrop Kevin L
Resumo: As infectious diseases continue to emerge, - as molecular techniques advance, the rheumatic manifestations of infectious diseases are increasingly recognized - better understood. Herein, we review important recent clinical, epidemiologic, - basic science advances within this area of rheumatology. We searched the U.S. National Library of Medicine PubMed database for relevant articles published since 1 January 2008. We identified a number of studies suggesting a potentially greater role for persistent viral - bacterial infections in the development of rheumatoid arthritis or rheumatoid arthritis-like syndromes. These include emerging pathogens like Chikungunya virus, as well as historically important pathogens like measles. New literature furthers the idea that antecedent infections with Chlamydia sp. could be causative in some cases of undifferentiated spondyloarthritis. Other studies document diagnostic methods capable of distinguishing between Hepatitis C virus - auto-immune driven arthritis allowing clinicians to better target therapy. Infectious pathogens are increasingly recognized in association with rheumatic disease. Rheumatologists should be aware of this trend as such recognition may alter the diagnosis - management of rheumatic symptoms, as well as trigger new research opportunities to better underst- the causes of rheumatic disease.
Palavras-Chave: Arthritis; Bacteria; Infection; Vasculitis; Virus
Imprenta: Current Opinion in Rheumatology, v. 22, n. 1, p. 72-77, 2010
Identificador do objeto digital: 10.1097/BOR.0b013e328333b9f5
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Autoimmunity ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya virus - Molecular methods ; Chikungunya Virus - Virus ; Chikungunya virus - Molecular screening ; Chikungunya virus - Immunology
Data de publicação: 2010
