Two Japanese siblings affected with Chikungunya fever with different clinical courses: Imported infections from the Cook Islands

Autor(es): Kondo Makoto, Akachi Shigehiro, Ando Katsuhiko, Nomura Tatsuma, Yamanaka Keiichi, Mizutani Hitoshi


Resumo: Two Japanese siblings visited the Cook Isl-s on business - stayed for 2 months. The sister developed a high fever, arthralgia, erythema - leg edema on the day after returning to Japan. The brother also developed neck - joint pain on the day following the sister's onset. Subsequently, his erythematous lesions spread over his whole body. Chikungunya virus was detected from the sister's blood - urine by specific reverse transcription polymerase chain reaction, but not in the brother's samples. Retrospectively, his history of Chikungunya fever was confirmed by the presence of the anti-Chikungunya virus immunoglobulin (Ig)M - IgG antibodies using the specific enzyme-linked immunoassay. In Japan, no autochthonous case of Chikungunya fever was reported previously. We should give attention to the imported infectious diseases for epidemic prevention. This report warns about the danger of the imported infectious diseases, - also suggests that covering the topic of infectious disease in the world is critical to doctors as well as travelers.


Palavras-Chave: Chikungunya fever; Chikungunya virus; Arthralgia; Imported infection; Tropical area


Imprenta: The Journal of Dermatology, v. 43, n. 6, p. 697-700, 2016


Identificador do objeto digital: 10.1111/1346-8138.13253


Descritores: Chikungunya virus - Antibodies ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemic


Data de publicação: 2016