Autor(es): Allain Jean-Pierre, Stramer Susan L, Carneiro-Proietti A B F, Martins M L, Lopes da Silva S N, Ribeiro M, Proietti F A, Reesink Henk W

Resumo: A spectrum of blood-borne infectious agents is transmitted through transfusion of infected blood donated by apparently healthy - asymptomatic blood donors. The diversity of infectious agents includes hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency viruses (HIV-1/2), human T-cell lymphotropic viruses (HTLV-I/II), Cytomegalovirus (CMV), Parvovirus B19, West Nile Virus (WNV), Dengue virus, trypanosomiasis, malaria, - variant CJD. Several strategies are implemented to reduce the risk of transmitting these infectious agents by donor exclusion for clinical history of risk factors, screening for the serological markers of infections, - nucleic acid testing (NAT) by viral gene amplification for direct - sensitive detection of the known infectious agents. Consequently, transfusions are safer now than ever before - we have learnt how to mitigate risks of emerging infectious diseases such as West Nile, Chikungunya, - Dengue viruses.

Palavras-Chave: Hepatitis; AIDS; West Nile virus; Dengue; Chagas disease

Imprenta: Biologicals, v. 37, n. 2, p. 71-77, 2009

Identificador do objeto digital: 10.1016/j.biologicals.2009.01.002

Descritores: Chikungunya virus - Cell ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology ; Chikungunya virus - Public health

Data de publicação: 2009

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