Autor(es): Petersen L R, Busch M P

Resumo: There exists considerable risk for transfusion transmission of arboviruses due to short periods of asymptomatic viraemia in populations with variable - sometimes extremely high incidence of arboviral infections. Aside from West Nile virus, few arbovirus transfusion transmissions have been proven, mostly due to difficulties in ruling out vector-borne transmission in recipients with arbovirus disease. Nevertheless, arbovirus transfusion risk models - assessments of viraemia prevalence in blood donations indicate substantial transfusion transmission of dengue - Chikungunya viruses in epidemic areas. Many other arboviruses, several of which are importation risks in the Americas, Europe - Asia, also cause large outbreaks - threaten transfusion safety. Prevention largely depends on excluding donors from outbreak areas or implementation of highly sensitive nucleic acid amplification tests. Because of the increasing emergence of arboviral disease globally, it is prudent to prepare for both endemic - exotic arboviruses capable of producing large epidemics - subsequent transfusion transmission risk.

Imprenta: Vox Sanguinis, v. 98, n. 4, p. 495-503, 2010

Identificador do objeto digital: 10.1111/j.1423-0410.2009.01286.x

Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Inflammation ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemic ; Chikungunya virus - Public health

Data de publicação: 2010

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