Tracking the re-emergence of epidemic Chikungunya virus in Indonesia
Autor(es): Laras Kanti, Sukri Nono C, Larasati Ria P, Bangs Michael J, Kosim Rizal, Djauzi , Wandra Tony, Master John, Kosasih Herman, Hartati Sri, Beckett Charmagne, Sedyaningsih Endang R, Beecham H James, Corwin Andrew L
Resumo: Twenty-four distinct outbreaks of probable chikungunya (CHIK) etiology were identified throughout Indonesia from September 2001 to March 2003, after a near 20-year hiatus of epidemic CHIK activity in the country. Thirteen outbreak reports were based on clinical observations alone, - 11 confirmed by serological/virological methods. Detailed epidemiological profiles of two investigated outbreaks in Bogor - Bekasi are presented. Human sera were screened using an ELISA for IgM - IgG anti-CHIK antibodies. Additionally, reverse transcriptase PCR - virus isolation were attempted for virus identification. The mean age of cases was 37 +/- 18 years in Bogor - 33 +/- 20 years in Bekasi. There was no outst-ing case-clustering, although outbreak-affected households were observed to be geographically grouped within villages. The attack rates in Bogor - Bekasi were 2.8/1000 - 6.7/1000 inhabitants respectively. Both outbreaks started in the rainy season following increased Aedes aegypti - A. albopictus densities.
Palavras-Chave: Chikungunya virus; Epidemic; Indonesia
Imprenta: Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 99, n. 2, p. 128-141, 2005
Identificador do objeto digital: 10.1016/j.trstmh.2004.03.013
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - RNA ; Chikungunya virus - Antibodies ; Chikungunya virus - Viral infections ; Chikungunya virus - RT-PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Epidemic ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology ; Chikungunya virus - Public health
Data de publicação: 2005
