The presence of antibody to Chikungunya and other serologically related viruses in the sera of sub-human primate imports to the United States

Autor(es): Harrison V R, Marshall J D, Guilloud N B


Resumo: Sera from 136 sub-human primates representing six genera were tested for the presence of antibody to Chikungunya, Semliki Forest Kumba strain, Onyong-nyong strain MP 87 and Mayaro strain B viruses. Twenty-six per cent of the sera tested were positive for N antibody to one or more of these agents. The extensive serologic overlap occurring between these viruses precluded any definitive interpretation of the results as to which virus may have been the specific infecting agent. Thirteen per cent of the sera tested were positive for CF and HI antibody to CHIK virus. In every instance a positive CF and HI response was associated with the presence of N antibody. Attempts at viral isolation from those sera of recent imports showing CF and HI antibody were unsuccessful.


Imprenta: Journal of Immunology, v. 98, n. 5, p. 979-981, 1967


Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Serology ; Chikungunya virus - Viral infections ; Chikungunya virus - Serology ; Chikungunya Virus - Virus ; Chikungunya virus - Immunology


Data de publicação: 1967