The molecular and cellular aspects of arthritis due to alphavirus infections: Lesson learned from Ross River virus
Autor(es): Rulli Nestor E, Melton Julian, Wilmes Anja, Ewart Gary, Mahalingam Suresh
Resumo: Alphaviruses such as the Sindbis-group viruses, Sc-inavian Ockelbo virus, the African Asian chikungunya virus, the African O'nyong-nyong virus, the South American Mayaro virus, - the Australasian Barmah Forest - Ross River viruses, are commonly associated with outbreaks of acute - persistent arthritis - arthralgia in humans. The mechanisms by which these viruses cause arthritis/arthralgia are poorly understood. This chapter summarizes our current underst-ing of viral arthritides using our newly developed mouse model of Ross River virus-induced joint - muscle inflammation.
Imprenta: Annals of the New York Academy of Sciences, v. 1102, p. 96-108, 2007
Identificador do objeto digital: 10.1196/annals.1408.007
Descritores: Chikungunya virus - Cytopathology ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Inflammation ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Molecular screening ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology
Data de publicação: 2007