Autor(es): St Geme J W, Horrigan D S, Toyama P S

Resumo: The purine analog, 6-mercaptopurine, failed to inhibit the synthesis and the action of interferon in primary chicken fetal cells. Actinomycin D, included as a positive control, completely blocked the synthesis and the action of interferon. Several aspects of host resistance to viral infection other than interferon are impaired by 6-mercaptopurine and delayed hypersensitivity may be the more important component.

Imprenta: Proceedings of the Society for Experimental Biology and Medicine, v. 130, n. 3, p. 852-855, 1969

Identificador do objeto digital: 10.3181/00379727-130-33671

Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Biosynthesis ; Chikungunya virus - Proteins ; Chikungunya virus - Cytokines ; Chikungunya Virus - Virus

Data de publicação: 1969