Structural proteins of Chikungunya virus
Autor(es): Simizu B, Yamamoto K, Hashimoto K, Ogata T
Resumo: Polyacrylamide gel analysis of the structural proteins of African - Asian strains of Chikungunya virus, an alphavirus, showed that both strains contain three structural proteins: glycosylated E1 - E2, embedded in the viral envelope, - a nonglycosylated nucleocapsid protein. In pulse-chase experiments the precursor protein PE2 was chased into glycoprotein E2, which migrated slightly faster than did glycoprotein E1. The third Chikungunya glycoprotein, E3, was not associated with mature virions but was released into culture fluids. With glycoproteins E1 - E2, separated by glass wool column chromatography, it was shown that hemagglutinating activity is associated with glycoprotein E1.
Imprenta: Journal of Virology, v. 51, n. 1, p. 254-258, 1984
Descritores: Chikungunya virus - Proteins ; Chikungunya Virus - Virus
Data de publicação: 1984
