Autor(es): Botros B A, Watts D M, Soliman A K, Salib A W, Moussa M I, Mursal H, Douglas C, Farah M

Resumo: Epidemics of a malaria-like illness affected several thous- residents of the Dam Camp, a refugee camp near Hargeysa in Somalia, during 1985, 1986, - 1987. The disease was characterized by fever, chills, sweats, headache, back - joint pains for as long as 10 days in some patients. Blood smears from acutely ill patients were negative for malaria. Of 28 acute - 10 convalescent sera tested by the indirect fluorescent antibody (IFA) - by the hemagglutination inhibition (HI) tests, all were negative for antibody to Rift Valley fever, Crimean-Congo hemorrhagic fever, Sindbis, Chikungunya, yellow fever, - Zika viruses. However, antibody reactive to dengue 2 virus was detected by the IFA test in 39% (15/38), - 11 of 29 (38%) of the same sera were antibody positive by the HI test. Also, IgG antibody reactive to dengue 2 was demonstrated in 60% (17/28) of the same sera by the enzyme immunoassay (EIA), - 14% (4/28) were positive for IgM antibody. Of ten patients for which acute - convalescent sera were available, two developed four fold or greater rises in antibody titer evidencing infection. These data suggested that dengue virus may have been the cause of the epidemic among the Dam Camp refugees.

Palavras-Chave: Dengue; ELISA; IgM antibody

Imprenta: Journal of Medical Virology, v. 29, n. 2, p. 79-81, 1989

Identificador do objeto digital: 10.1002/jmv.1890290202

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Viral infections ; Chikungunya virus - Serological diagnosis ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemic ; Chikungunya virus - Immunology ; Chikungunya virus - Public health ; Chikungunya virus - Zika fever

Data de publicação: 1989

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