Retrospective seroepidemiological study of chikungunya infection in South Asia, Southeast Asia and the Pacific region
Autor(es): Ngwe Tun M M, Inoue S, Thant K Z, Talemaitoga N, Aryati A, Dimaano E M, Matias R R, Buerano C C, Natividad F F, Abeyewickreme W, Thuy N T T, Mai L T Q, Hasebe F, Hayasaka D, Morita K
Resumo: Chikungunya virus (CHIKV) - Ross River virus (RRV) of the genus Alphavirus, family Togaviridae are mainly transmitted by Aedes mosquitoes - the symptoms they cause in patients are similar to dengue. A chikungunya (CHIK) outbreak re-emerged in several Asian countries during 2005-2006. This study aimed to clarify the prevalence of CHIKV infection in suspected dengue patients in six countries in South Asia - Southeast Asia. Seven hundred forty-eight serum samples were from dengue-suspected patients in South Asia - Southeast Asia, - 52 were from patients in Fiji. The samples were analysed by CHIKV IgM capture ELISA, CHIKV IgG indirect ELISA - focus reduction neutralization test against CHIKV or RRV. CHIK-confirmed cases in South Asia, particularly Myanmar - Sri Lanka, were 4·6%, - 6·1%, respectively; - in Southeast Asia, particularly Indonesia, the Philippines - Vietnam, were 27·4%, 26·8% - 25·0%, respectively. It suggests that CHIK was widely spread in these five countries in Asia. In Fiji, no CHIK cases were confirmed; however, RRV-confirmed cases represented 53·6% of suspected dengue cases. It suggests that RRV is being maintained or occasionally entering from neighbouring countries - should be considered when determining a causative agent for dengue-like illness in Fiji.
Palavras-Chave: Asia; Fiji; Ross River virus; Chikungunya virus; Seroepidemiology
Imprenta: Epidemiology and Infection, v. 144, n. 11, p. 2268-2275, 2016
Identificador do objeto digital: 10.1017/S095026881600056X
Descritores: Chikungunya virus - Dengue
Data de publicação: 2016
