Autor(es): Naresh Kumar C V M, Sai Gopal D V R

Resumo: Chikungunya virus (CHIKV), a reemerging arboviral disease of public health concern is characterized by a triad of fever, rash - arthralgia. It was responsible for a number of epidemics in Asia - Africa. The severity of the current epidemic can be judged by the fact that an estimated 1.38 million people in India - one-third of the La Reunion population (by April 2006) were affected by CHIKV. Aedes aegypti - Aedes albopictus are the major mosquitoes transmitting CHIKV in Asia. Various neurological complications - CHIKV associated deaths were encountered during the current outbreak (2005-2010). The aggressive nature of the recent CHIKV epidemic was attributed to the mutations in the viral genome in addition to their adaptation - spread to vectors like Aedes albopictus. Proper diet, adequate rest - symptomatic treatment using non-salicylate analgesics - Non-steroidal anti inflammatory drugs (NSAIDS) helped the patients in recovering from CHIKV infections. In the absence of an effective vaccine, rapid implementation of mosquito control measures - establishment of a system for continuous surveillance of the disease seems to be the only possible solution to prevent any such outbreak in the near future.

Palavras-Chave: Aedes mosquito; CHIKV; Co-infection; Differential diagnosis; Mutation; RT-PCR; Vaccine

Imprenta: Indian Journal of Virology, v. 21, n. 1, p. 8-17, 2010

Identificador do objeto digital: 10.1007/s13337-010-0012-1

Descritores: Chikungunya virus - Genome ; Chikungunya virus - Viral infections ; Chikungunya virus - RT-PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Vaccine ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemic ; Chikungunya virus - Public health

Data de publicação: 2010

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