Presence of autoimmune antibody in chikungunya infection

Autor(es): Maek-A-Nantawat Wirach, Silachamroon Udomsak


Resumo: Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thail-. Recently, Southern Thail- was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness - swelling of the limbs. During the investigation to exclude autoimmune muscular inflammation, high titers of antinuclear antibody were detected. This is the report of autoimmunity detection associated with an arbovirus infection. The symptoms can mimic autoimmune polymyositis disease, - the condition requires close monitoring before deciding to embark upon prolonged specific treatment with immunomodulators.


Imprenta: Case Reports in Medicine, v. 2009, p. 840183, 2009


Identificador do objeto digital: 10.1155/2009/840183


Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Autoimmunity ; Chikungunya virus - Inflammation ; Chikungunya Virus - Virus


Data de publicação: 2009