Autor(es): Blacksell Stuart D, Tanganuchitcharnchai Ampai, Jarman Richard G, Gibbons Robert V, Paris Daniel H, Bailey Mark S, Day Nicholas P J, Premaratna Ranjan, Lalloo David G, de Silva H Janaka

Resumo: A Sri Lankan fever cohort (n = 292 patients; 17.8% prevalence) was used to assess two st-ard diagnostic Chikungunya IgM tests. The immunochromatographic test (ICT) acute sample sensitivity (SN) was 1.9 to 3.9%, - specificity (SP) was 92.5 to 95.0%. The enzyme-linked immunosorbent assay (ELISA) gave an acute sample SN of 3.9% - an SP of 92.5% - a convalescent sample SN of 84% - an SP of 91%. These assays are not suitable for the acute diagnosis of Chikungunya virus infection.

Imprenta: Clinical and Vaccine Immunology, v. 18, n. 10, p. 1773-1775, 2011

Identificador do Objeto Digital: 10.1128/CVI.05288-11

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Vaccine ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Immunology ; Chikungunya virus - Public health

Data de Publicação: 2011