Autor(es): Mahendradas Padmamalini, Ranganna Shylaja K, Shetty Rohit, Balu Ramgopal, Narayana Kannan M, Babu Rajesh B, Shetty Bhujang K

Resumo: To report ocular manifestations associated with chikungunya. Retrospective, nonr-omized, observational case series. Nine chikungunya patients with ocular involvement. All patients with chikungunya infection presenting with ocular complaints from September 2006 to October 2006 were included in the study. The infection was confirmed by demonstration of chikungunya immunoglobulin M antibody in sera of all patients. All patients underwent an ophthalmic examination including fundus photography, fundus fluorescein angiography, confocal microscopy of keratic precipitates, - optical coherence tomography. Positive ocular changes were recorded - tabulated. Characteristics, frequency, - locations of ocular lesions found in the participants. There were 9 patients with ocular lesions; 1 had nodular episcleritis, 5 presented with acute iridocyclitis, - 3 had retinitis. Four to 12 weeks before the development of ocular manifestations, all of these patients had fever. Although there were no specific changes of iridocyclitis that were diagnostic of the fever, the retinal changes were consistent with viral retinitis. All patients recovered from the infection with relatively good vision. It appears that iridocyclitis - retinitis are the most common ocular manifestations associated with chikungunya, with a typically benign clinical course. Less frequent ocular lesions include episcleritis. All the patients responded well to the treatment with preservation of good vision. To the best of our knowledge, similar ocular manifestations associated with chikungunya infection have not been reported. In the differential diagnosis of iridocyclitis - retinitis with features suggestive of a viral infection, the entity of chikungunya-associated ocular changes should be considered in the regions affected by the epidemic.

Imprenta: Ophthalmology, v. 115, n. 2, p. 287-291, 2008

Identificador do objeto digital: 10.1016/j.ophtha.2007.03.085

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Viral infections ; Chikungunya virus - Clinical examination ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemic ; Chikungunya virus - Immunology ; Chikungunya virus - Public health

Data de publicação: 2008

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