Novel infectious agents causing uveitis
Autor(es): Khairallah Moncef, Chee Soon Phaik, Rathinam Sivakumar R, Attia Sonia, Nadella Venu
Resumo: In any patient with uveitis, an infectious cause should be ruled out first. The differential diagnosis includes multiple well-known diseases including herpes, syphilis, toxoplasmosis, tuberculosis, bartonellosis, Lyme disease, - others. However, clinician should be aware of emerging infectious agents as potential causes of systemic illness - also intraocular inflammation. Air travel, immigration, - globalization of business have overturned traditional pattern of geographic distribution of infectious diseases, - therefore one should work locally but think globally. This review recapitulates the systemic - ocular manifestations of several emergent infectious diseases relevant to the ophthalmologist including Rickettsioses, West Nile virus infection, Rift valley fever, Dengue fever, - Chikungunya. Retinitis, chorioretinitis, retinal vasculitis, - optic nerve involvement have been associated with these emergent infectious diseases. The diagnosis of any of these infections is usually based on pattern of uveitis, systemic symptoms - signs, - specific epidemiological data - confirmed by detection of specific antibody in serum. A systematic ocular examination, showing fairly typical fundus findings, may help establish an early clinical diagnosis, which allows prompt, appropriate management.
Palavras-Chave: Uveitis; Infection; Emergent infectious diseases; Rickettsioses; West Nile virus; Rift valley fever; Dengue fever; Chikungunya; Retinitis; Chorioretinitis; Retinal vasculitis; Optic nerve involvement
Imprenta: International Ophthalmology, v. 30, n. 5, p. 465-483, 2010
Identificador do objeto digital: 10.1007/s10792-009-9319-6
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Inflammation ; Chikungunya virus - Viral infections ; Chikungunya virus - Clinical examination ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue
Data de publicação: 2010
