Autor(es): Gandhi M R, Reegan A D, Ganesan P, Sivasankaran K, Paulraj M G, Balakrishna K, Ignacimuthu S, Al-Dhabi N A

Resumo: The mosquitocidal activities of different fractions - a compound alizarin from the methanol extract of Rubia cordifolia roots were evaluated on larvae - pupae of Culex quinquefasciatus Say - Aedes aegypti (L.) (Diptera: Culicidae). Larvae - pupae were exposed to concentrations of 2.5, 5.0, 7.5 - 10 ppm for fractions - 0.5, 1.0, 1.5 - 2.0 ppm for compound. After 24 h, the mortality was assessed - the LC50 - LC90 values were estimated for larvae - pupae. Among the 23 fractions screened, fraction 2 from the methanol extract of R. cordifolia showed good mosquitocidal activity against C. quinquefasciatus - A. aegypti. LC50 - LC90 values of fraction 2 were 3.53 - 7.26 ppm for C. quinquefasciatus - 3.86 - 8.28 ppm for A. aegypti larvae, - 3.76 - 7.50 ppm for C. quinquefasciatus - 3.92 - 8.05 ppm for A. aegypti pupae, respectively. Further, the isolated compound alizarin presented good larvicidal - pupicidal activities. LC50 - LC90 values of alizarin for larvae were 0.81 - 3.86 ppm against C. quinquefasciatus - 1.31 - 6.04 ppm for A. aegypti larvae, respectively. Similarly, the LC50 - LC90 values of alizarin for pupae were 1.97 - 4.79 ppm for C. quinquefasciatus - 2.05 - 5.59 ppm for A. aegypti pupae, respectively. The structure of the isolated compound was identified on the basis of spectroscopic analysis - compared with reported spectral data. The results indicated that alizarin could be used as a potential larvicide - pupicide.

Palavras-Chave: Bioassay; Zika virus; Chikungunya; Dengue; Lymphatic filariasis; Mosquito control; Sustainable pest control; Vector control

Imprenta: Neotropical Entomology, v. 45, n. 4, p. 441-448, 2016

Identificador do Objeto Digital: 10.1007/s13744-016-0386-x

Descritores: Chikungunya Virus - Virus ; Chikungunya virus - Larvicide ; Chikungunya virus - Dengue

Data de Publicação: 2016