Inhibitory effect of mononucleotides on virus plaque formation
Autor(es): Gifford G E
Resumo: Alkaline hydrolysates of yeast ribonucleic acid were found to inhibit markedly plaque formation by vaccinia and chikungunya viruses in chick embryo fibroblast monolayers. Mononucleotides were subsequently implicated and shown to inhibit vaccinia virus plaque formation. Adenosine monophosphate was the most effective of the nucleotides tested in inhibiting vaccinia virus and the inhibition could be reversed with mixtures of the mononucleotides.
Imprenta: Proceedings of the Society for Experimental Biology and Medicine, v. 119, p. 9-12, 1965
Identificador do objeto digital: 10.3181/00379727-119-30083
Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Cell ; Chikungunya virus - RNA ; Chikungunya Virus - Virus
Data de publicação: 1965
