Infectious causes of encephalitis and meningoencephalitis in Thailand, 2003-2005
Autor(es): Olsen Sonja J, Campbell Angela P, Supawat Krongkaew, Liamsuwan Sahas, Chotpitayasunondh Tawee, Laptikulthum Somsak, Viriyavejakul Akravudh, Tantirittisak Tasanee, Tunlayadechanont Supoch, Visudtibhan Anannit, Vasiknanonte Punnee, Janjindamai Supachai, Boonluksiri Pairoj, Rajborirug Kiatsak, Watanaveeradej Veerachai, Khetsuriani Nino, Dowell Scott F
Resumo: Acute encephalitis is a severe neurologic syndrome. Determining etiology from among ?100 possible agents is difficult. To identify infectious etiologies of encephalitis in Thail-, we conducted surveillance in 7 hospitals during July 2003-August 2005 - selected patients with acute onset of brain dysfunction with fever or hypothermia - with abnormalities seen on neuroimages or electroencephalograms or with cerebrospinal fluid pleocytosis. Blood - cerebrospinal fluid were tested for >30 pathogens. Among 149 case-patients, median age was 12 (range 0-83) years, 84 (56%) were male, - 15 (10%) died. Etiology was confirmed or probable for 54 (36%) - possible or unknown for 95 (64%). Among confirmed or probable etiologies, the leading pathogens were Japanese encephalitis virus, enteroviruses, - Orientia tsutsugamushi. No samples were positive for chikungunya, Nipah, or West Nile viruses; Bartonella henselae; or malaria parasites. Although a broad range of infectious agents was identified, the etiology of most cases remains unknown.
Imprenta: Emerging Infectious Diseases, v. 21, n. 2, p. 280-289, 2015
Identificador do objeto digital: 10.3201/eid2102.140291
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2015
