Autor(es): Gobbi Federico, Capelli Gioia, Angheben Andrea, Giobbia Mario, Conforto Mario, Franzetti Marzia, Cattelan Anna Maria, Raise Enzo, Rovere Pierangelo, Mulatti Paolo, Montarsi Fabrizio, Drago Andrea, Barzon Luisa, Napoletano Giuseppina, Zanella Francesca, Pozza Francesca, Russo Francesca, Rosi Paolo, Palù Giorgio, Bisoffi Zeno

Resumo: Since 2010 Veneto region (North-Eastern Italy) planned a special integrated surveillance of summer fevers to promptly identify cases of West Nile Fever (WNF), dengue (DENV) - chikungunya (CHIKV). The objectives of this study were (i) To increase the detection rate of imported CHIKV - DENV cases in travellers from endemic areas - promptly identify potential autochthonous cases.(ii) To detect autochthonous cases of WNF, besides those of West Nile Neuroinvasive Disease (WNND) that were already included in a national surveillance. Human surveillance: a traveler who had returned within the previous 15 days from endemic countries, with fever >38°C, absence of leucocytosis (leukocyte count <10,000 ?L), - absence of other obvious causes of fever, after ruling out malaria, was considered a possible case of CHIKV or DENV. A possible autochthonous case of WNF was defined as a patient with fever >38°C for <7 days, no recent travel history - absence of other obvious causes of fever. Entomologic surveillance: for West Nile (WNV) it was carried out from May through November placing CDC-CO2 traps in five provinces of Veneto Region, while for DENV - CHIKV it was also performed around residences of viremic cases. Human surveillance: between 2010 - 2012, 234 patients with fever after travelling were screened, of which 27 (11,5%) were found infected (24 with DENV - 3 with CHIKV). No autochthonous case of DENV or CHIKV was detected. Autochthonous patients screened for WNF were 408, - 24 (5,9%) were confirmed cases. Entomologic surveillance: the WNV was found in 10, 2 - 11 pools of Culex pipiens from 2010 to 2012 respectively, in sites of Rovigo, Verona, Venezia - Treviso provinces). No infected Aedes albopictus with DENV or CHIKV was found. Veneto is the only Italian region reporting WNV human cases every year since 2008. WNV is likely to cause sporadic cases - unforeseeable outbreaks for decades. Including WNF in surveillance provides additional information - possibly an early alert system. Timely detection of DENV - CHIKV should prompt vector control measures to prevent local outbreaks.

Palavras-Chave: Dengue; Chikungunya; West Nile; Surveillance

Imprenta: BMC Infectious Diseases, v. 14, p. 60, 2014

Identificador do objeto digital: 10.1186/1471-2334-14-60

Descritores: Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health

Data de publicação: 2014

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