Household-based sero-epidemiologic survey after a yellow fever epidemic, Sudan, 2005

Autor(es): Farnon Eileen C, Gould L Hannah, Griffith Kevin S, Osman Magdi S, Kholy Amgad El, Brair Maria-Emanuela, Panella Amanda J, Kosoy Olga, Laven Janeen J, Godsey Marvin S, Perea William, Hayes Edward B


Resumo: From September through early December 2005, an outbreak of yellow fever (YF) occurred in South Kordofan, Sudan, resulting in a mass YF vaccination campaign. In late December 2005, we conducted a serosurvey to assess YF vaccine coverage - to better define the epidemiology of the outbreak in an index village. Of 552 persons enrolled, 95% reported recent YF vaccination, - 25% reported febrile illness during the outbreak period: 13% reported YF-like illness, 4% reported severe YF-like illness, - 12% reported chikungunya-like illness. Of 87 persons who provided blood samples, all had positive YF serologic results, including three who had never been vaccinated. There was also serologic evidence of recent or prior chikungunya virus, dengue virus, West Nile virus, - Sindbis virus infections. These results indicate that YF virus - chikungunya virus contributed to the outbreak. The high prevalence of YF antibody among vaccinees indicates that vaccination was effectively implemented in this remotely located population.


Imprenta: The American Journal of Tropical Medicine and Hygiene,v. 82, n. 6, p. 1146-1152, 2010


Identificador do objeto digital: 10.4269/ajtmh.2010.09-0105


Descritores: Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Vaccine ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemic ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health


Data de publicação: 2010