Entomological investigation and control of a chikungunya cluster in Singapore
Autor(es): Tan Cheong Huat, Wong Pei Sze Jeslyn, Li Mei Zhi Irene, Tan Siok Yin Sharon, Lee Tze Kwang Caleb, Pang Sook Cheng, Lam-Phua Sai Gek, Maideen Nasir, Png Ah Bah, Koou Sin Ying, Lu Deng, Ng Lee-Ching
Resumo: In August 2008, a team from the National Environmental Agency conducted an entomological investigation of a chikungunya cluster in Singapore, with the primary aim of identifying the vector responsible for the outbreak - to assess the vector control operation. A total of 173 adult mosquitoes were caught using both the sweep-net method - the BG Sentinel Traps in - around the affected workers' quarters. Of these, 120 (69.4%) were Aedes albopictus - the rest were Culex quinquefasciatus. More than 2700 Ae. albopictus larvae were also collected from 33 breeding habitats detected. No Aedes aegypti was found. During the preintervention period, 6 (8.4%) out of 71 adult female Ae. albopictus were found positive for the chikungunya virus (CHIKV). Vector control measures resulted in a 90% reduction of adult Ae. albopictus caught by BG Sentinel Traps. Postintervention surveillance revealed the presence of CHIKV-positive mosquitoes. These findings led to continued intensive vector control operation in the affected area that further reduced vector population - interrupted the transmission of the disease. The E1 gene sequence of the CHIKV was identical to those of CHIKV isolated from human chikungunya cases working in the affected area, - contained the A226V mutation. The incrimination of Ae. albopictus as a major vector involved in the transmission of A226V CHIKV had led to the revision of chikungunya control strategy in Singapore. This study suggests the benefit of a vector control program that includes the evaluation of control measures in conjunction to virological surveillance in vector population.
Imprenta: Vector Borne and Zoonotic Diseases, v. 11, n. 4, p. 383-390, 2011
Identificador do objeto digital: 10.1089/vbz.2010.0022
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya virus - RT-PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2011
