Entomologic investigations of a Chikungunya virus epidemic in the Union of the Comoros, 2005
Autor(es): Sang Rosemary C, Ahmed Ouledi, Faye Ousmane, Kelly Cindy L H, Yahaya Ali Ahmed, Mmadi Ibrahim, Toilibou Ali, Sergon Kibet, Brown Jennifer, Agata Naftali, Yakouide Allarangar, Ball Mamadou D, Breiman Robert F, Miller Barry R, Powers Ann M
Resumo: From January to April 2005, an epidemic of chikungunya virus (CHIKV) illness occurred in the Union of Comoros. Entomological studies were undertaken during the peak of the outbreak, from March 11 to March 31, aimed at identifying the primary vector(s) involved in transmission so that appropriate public health measures could be implemented. Adult mosquitoes were collected by backpack aspiration - human l-ing collection in homes - neighborhoods of clinically ill patients. Water-holding containers were inspected for presence of mosquito larvae. Adult mosquitoes were analyzed by RT-PCR - cultivation in cells for the presence of CHIK virus -/or nucleic acid. A total of 2,326 mosquitoes were collected - processed in 199 pools. The collection consisted of 62.8% Aedes aegypti, 25.5% Culex species, - 10.7% Aedes simpsoni complex, Eretmapodites spp - Anopheles spp. Seven mosquito pools were found to be positive for CHIKV RNA - 1 isolate was obtained. The single CHIKV mosquito isolate was from a pool of Aedes aegypti - the minimum infection rate (MIR) for this species was 4.0, suggesting that Ae. aegypti was the principal vector responsible for the outbreak. This was supported by high container (31.1%), household (68%), - Breteau (126) indices, with discarded tires (58.8%) - small cooking - water storage vessels (31.1%) registering the highest container indices.
Imprenta: The American Journal of Tropical Medicine and Hygiene, v. 78, n. 1, p. 77-82, 2008
Descritores: Chikungunya virus - Cell ; Chikungunya virus - Pathogenesis ; Chikungunya virus - RNA ; Chikungunya virus - Viral infections ; Chikungunya virus - RT-PCR ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Epidemic ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2008
