Emergence of Chikungunya virus infection in Orissa, India

Autor(es): Dwibedi Bhagirathi, Mohapatra Namita, Beuria Mihir K, Kerketta Anna S, Sabat Jyotsna, Kar Shantanu K, Rao Epari V, Hazra Rupensu K, Parida Sarat K, Marai Nitisheel


Resumo: From September through October 2006, an unknown disease characterized by acute onset of fever, joint pain with or without swelling, - maculopapular rash along with fatigue was reported from three villages of Cuttack - one village of Kendrapara district of Orissa, India, by the State Health Department. Upon learning this, a team from Regional Medical Research Centre (Indian Council of Medical Research), Bhubaneswar, Orissa, conducted an epidemiological investigation in the area. Household survey was carried out - clinical examination of the symptomatic individuals (n = 1289: Kendrapara, 752; Cuttack, 537) undertaken. Based on the recorded chikungunya (CHIK) fever symptoms, a vector-borne viral disease was considered for provisional diagnosis. Blood samples were collected from 217 symptomatic individuals; to confirm the diagnosis, sera were tested for anti-CHIK antibody (immunoglobulin M), which revealed 63% (64/101) - 40% (47/116) seropositivity in the samples from Kendrapara - Cuttack district, respectively. The illness was managed with analgesics like paracetamol. No death was recorded due to the illness. Entomological survey in the areas revealed the presence of Aedes mosquitoes: aegypti, albopictus, - vittatus. The per-man-hour density of Aedes vectors ranged from 0.8 to 7.6. High larval indices, house index >17% - Breteau index >70%, also indicated Aedes breeding in the area. The investigation documented circulation of CHIK in Orissa, India, - helped to take preventive steps in the outbreak area, with the suggested vector control measures.


Imprenta: Vector Borne and Zoonotic Diseases, v. 10, n. 4, p. 347-354, 2010


Identificador do objeto digital: 10.1089/vbz.2008.0190


Descritores: Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya virus - Clinical examination ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health ; Chikungunya virus - Rash maculopapular


Data de publicação: 2010