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Emergence of Chikungunya virus infection in Orissa, India

Autor(es)Dwibedi Bhagirathi, Mohapatra Namita, Beuria Mihir K, Kerketta Anna S, Sabat Jyotsna, Kar Shantanu K, Rao Epari V, Hazra Rupensu K, Parida Sarat K, Marai Nitisheel
ResumoFrom September through October 2006, an unknown disease characterized by acute onset of fever, joint pain with or without swelling, - maculopapular rash along with fatigue was reported from three villages of Cuttack - one village of Kendrapara district of Orissa, India, by the State Health Department. Upon learning this, a team from Regional Medical Research Centre (Indian Council of Medical Research), Bhubaneswar, Orissa, conducted an epidemiological investigation in the area. Household survey was carried out - clinical examination of the symptomatic individuals (n = 1289: Kendrapara, 752; Cuttack, 537) undertaken. Based on the recorded chikungunya (CHIK) fever symptoms, a vector-borne viral disease was considered for provisional diagnosis. Blood samples were collected from 217 symptomatic individuals; to confirm the diagnosis, sera were tested for anti-CHIK antibody (immunoglobulin M), which revealed 63% (64/101) - 40% (47/116) seropositivity in the samples from Kendrapara - Cuttack district, respectively. The illness was managed with analgesics like paracetamol. No death was recorded due to the illness. Entomological survey in the areas revealed the presence of Aedes mosquitoes: aegypti, albopictus, - vittatus. The per-man-hour density of Aedes vectors ranged from 0.8 to 7.6. High larval indices, house index >17% - Breteau index >70%, also indicated Aedes breeding in the area. The investigation documented circulation of CHIK in Orissa, India, - helped to take preventive steps in the outbreak area, with the suggested vector control measures.
ImprentaVector Borne and Zoonotic Diseases, v. 10, n. 4, p. 347-354, 2010
Identificador do Objeto Digital10.1089/vbz.2008.0190
DescritoresChikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya virus - Clinical examination ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health ; Chikungunya virus - Rash maculopapular
Data de Publicação:2010