Electron microscope study of development of Chikungunya virus in green monkey kidney stable (VERO) cells

Autor(es): Higashi N, Matsumoto A, Tabata K, Nagatomo Y


Resumo: In an electron microscope study, Chikungunya virus (CHV) grown in VERO cell cultures revealed a shape, size, and structure characteristic of members of the arbovirus group. In thin sections, the virus displayed a roughly spherical or somewhat polygonal profile with a mean diameter of 42 m?, and consisted of a 25 to 30-m? core, exhibing substructures in the form of fine dots and thread-like elements, separated by a zone of diminished density from a well-defined envelope having fine projections. Intracytoplasmic, characteristic, dense particles 22 to 25 m? in diameter having the same substructures as the viral core were presumed to represent virus precursors.


Imprenta: Virology, v. 33, n. 1, p. 55-69, 1967


Identificador do objeto digital: 10.1016/0042-6822(67)90093-1


Descritores: Chikungunya virus - Cell ; Chikungunya virus - Proteins ; Chikungunya Virus - Virus


Data de publicação: 1967