Dengue-type viruses isolated in Singapore

Autor(es): LIM K A, CHAN Y C, PHOON W O, HANAM E


Resumo: A dengue-like illness with marked haemorrhagic manifestations appeared in Singapore in 1960. Its similarity in many respects to the haemorrhagic fevers of Thail- - the Philippines led to its being described as Singapore haemorrhagic fever".This paper describes the isolation - identification of dengue-type viruses from patients in Singapore between 1960 - 1962. In addition to the conventional complement-fixation - neutralization tests, a new test, called the "sensitized erythrocyte agglutination test", was employed; this test method is described.Altogether 21 dengue-type viruses were isolated, including dengue types 1, 2 - 4. Chikungunya virus, prominent in the Thail- disease, was not detected.The author suggests that study of the epidemiology of haemorrhagic fevers in South-East Asia would cast further light on the transmission of arboviruses."


Palavras-Chave: Arbovirus; Complement fixation test; Dengue; Neutralization test; Singapore


Imprenta: Bulletin of the World Health Organization, v. 30, p. 227-240, 1964


Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Serology ; Chikungunya virus - Viral infections ; Chikungunya virus - Serology ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology


Data de publicação: 1964