Autor(es): Babu Kalpana, Kini Raghuvir, Philips Mariamma, Subbakrishna D K

Resumo: To analyze the clinic profile of polymerase chain reaction proven viral anterior uveitis in a south Indian patient population. Retrospective, nonr-omized study between January 2009 - July 2012. Out of the 36 patients with polymerase chain reaction (PCR)-positive viral anterior uveitis, 24 patients had varicella zoster virus (VZV) anterior uveitis, 7 patients had HSV anterior uveitis, 3 patients had cytomegalovirus (CMV) anterior uveitis, - 2 patients had chikungunya virus related anterior uveitis. Corneal involvement was seen in 21 cases (58.33%). An altered iris pattern was seen in 14 cases (38.89%). Increase in intraocular pressure (IOP) at the time of inflammation was seen in 10 cases (27.78%). Reactivations were seen in 22 cases (61.11%). A comparison of herpes simplex virus (HSV)- - VZV-related anterior uveitis did not reveal any significant factors except for a previous history of herpes zoster in VZV-associated uveitis. We see isolated viral anterior uveitis related to HSV, VZV, CMV, - chikungunya viruses in our patient population. Corneal involvement, pigmented keratic precipitates, an abnormal iris pattern, increase in IOP, - reactivations are seen as a spectrum of viral anterior uveitis in our patient population as well.

Palavras-Chave: Anterior uveitis; PCR; Cytomegalovirus; Herpes simplex; Varicella zoster

Imprenta: Ocular Immunology and Inflammation, v. 22, n. 5, p. 356-359, 2014

Identificador do objeto digital: 10.3109/09273948.2013.841482

Descritores: Chikungunya virus - DNA ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Inflammation ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health

Data de publicação: 2014

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