Clinical profile of chikungunya sequelae, association with obesity and rest during acute phase
Autor(es): Padmakumar B, Jayan Jacob B, Menon Rejeesh, Kottarathara Arun Jose
Resumo: The scarcity of literature regarding chikungunya infection sequelae makes it an unexplored area of medicine. We analyzed 1,111 patients with confirmed chikungunya sequelae - found a female predominance in those with sequelae which increased with age up to 40-50 years old, then decreased with further increase in age. In males age > 60 years old was the predominant age group affected. The symptoms were mainly symmetrical polyarthralgia of the proximal - distal interphalangeal joints. Dermatological manifestations were mainly hyper pigmented patches, generalized pruritus, - a maculopapular rash. Insomnia, fatigability - headache may indicate neurological involvement. Obesity gave an odds ratio of 2.07 for risk of arthritis. There was no significant benefit from rest during the acute phase (p < 0.001) of chikungunya in preventing chronicity of sequelae. Obesity as an independent risk factor for chronicity of chikungunya infection sequelae is a new finding.
Palavras-Chave: Chikungunya sequelae; Obesity; Rest; Acute phase
Imprenta: The Southeast Asian Journal of Tropical Medicine and Public Health, v. 41, n. 1, p. 85-91, 2010
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya virus - Clinical examination ; Chikungunya Virus - Virus ; Chikungunya virus - Public health ; Chikungunya virus - Rash maculopapular
Data de publicação: 2010
