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Clinical profile of chikungunya sequelae, association with obesity and rest during acute phase

Autor(es)Padmakumar B, Jayan Jacob B, Menon Rejeesh, Kottarathara Arun Jose
ResumoThe scarcity of literature regarding chikungunya infection sequelae makes it an unexplored area of medicine. We analyzed 1,111 patients with confirmed chikungunya sequelae - found a female predominance in those with sequelae which increased with age up to 40-50 years old, then decreased with further increase in age. In males age > 60 years old was the predominant age group affected. The symptoms were mainly symmetrical polyarthralgia of the proximal - distal interphalangeal joints. Dermatological manifestations were mainly hyper pigmented patches, generalized pruritus, - a maculopapular rash. Insomnia, fatigability - headache may indicate neurological involvement. Obesity gave an odds ratio of 2.07 for risk of arthritis. There was no significant benefit from rest during the acute phase (p < 0.001) of chikungunya in preventing chronicity of sequelae. Obesity as an independent risk factor for chronicity of chikungunya infection sequelae is a new finding.
Palavras-ChaveChikungunya sequelae; Obesity; Rest; Acute phase
ImprentaThe Southeast Asian Journal of Tropical Medicine and Public Health, v. 41, n. 1, p. 85-91, 2010
DescritoresChikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya virus - Clinical examination ; Chikungunya Virus - Virus ; Chikungunya virus - Public health ; Chikungunya virus - Rash maculopapular
Data de Publicação:2010