Autor(es): Tortosa P, Courtiol A, Moutailler S, Failloux A-B, Weill M

Resumo: A severe Chikungunya (CHIK) outbreak recently hit several countries of the Indian Ocean. On La Réunion Isl-, Aedes albopictus was incriminated as the major vector. This mosquito species is naturally co-infected with two distinct strains of the endosymbiont Wolbachia, namely wAlbA - wAlbB, which are increasingly attracting interest as potential tools for vector control. A PCR quantitative assay was developed to investigate Wolbachia/mosquito host interactions. We show that Wolbachia densities are slightly decreased in CHIK virus (CHIKV)-infected females. We measured the impact of CHIKV replication on a lysogenic virus: WO bacteriophage. Our data indicate that WO is sheltered by wAlbB, likely at a single copy per bacteria, - that CHIKV replication is not a physiological stress triggering WO entrance into the lytic cycle.

Imprenta: Insect Molecular Biology, v. 17, n. 6, p. 677-684, 2008

Identificador do Objeto Digital: 10.1111/j.1365-2583.2008.00842.x

Descritores: Chikungunya virus - DNA ; Chikungunya virus - Pathogenesis ; Chikungunya Virus - Virus ; Chikungunya virus - Public health

Data de Publicação: 2008