Autor(es): Scripsema Nicole K, Sharifi Emile, Samson C Michael, Kedhar Sanjay, Rosen Richard B

Resumo: To report the first known case of bilateral granulomatous panuveitis secondary to chikungunya fever in the United States, acquired by a U.S. citizen traveling from an endemic region. Case report. A 47-year-old woman presented with 10 days of bilateral decreased vision - photophobia concurrent with a febrile illness contracted while visiting the Dominican Republic. She presented with bilateral granulomatous panuveitis - exudative retinal detachments. Extensive workup was negative with the exception of positive chikungunya virus immunoglobulin G - immunoglobulin M titers. Initially, she responded to corticosteroid treatment but developed recurrent inflammation 3 months after completing the initial treatment. Immunomodulatory therapy was initiated at the time of recurrence, - with immunomodulatory therapy alone her inflammation has been controlled for 6 months. The prevalence of chikungunya fever-related uveitis is increasing with the recent epidemics throughout the Americas. Inflammation can occur during the febrile illness or months later - can manifest in a variety of ways. Posterior segment inflammation is more commonly a delayed presentation. Previous reports suggest that chikungunya fever-related uveitis responds well to corticosteroid therapy. This is the first reported case of recurrent inflammation. Given the wide variety of presentations, chikungunya fever-related uveitis should be included in the differential diagnosis of all at-risk patients presenting with acute ocular inflammation, particularly those traveling from endemic regions.

Imprenta: Retinal Cases & Brief Reports, v. 9, n. 4, p. 352-356, 2015

Identificador do objeto digital: 10.1097/ICB.0000000000000232

Descritores: Chikungunya virus - Inflammation ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemic

Data de publicação: 2015