Chikungunya virus-associated death in Malaysia

Autor(es): Sam I C, Kamarulzaman A, Ong G S Y, Veriah R S, Ponnampalavanar S, Chan Y F, AbuBakar S


Resumo: Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which causes fever, rash, - arthralgia. In the past, life-threatening complications were very rarely reported. However, during the recent worldwide outbreaks, there have been several reports of unusually severe complications - deaths. Malaysia is experiencing a nationwide outbreak of CHIKV, with over 10 000 patients affected since April 2008. We report the first case of culture-confirmed CHIKV-associated death in Malaysia, in a patient with fever, rash, acute exacerbation of pre-existing heart failure, rhabdomyolysis, - multiple organ failure. CHIKV infections may cause atypical, severe or fatal presentations.


Imprenta: Tropical Biomedicine, v. 27, n. 2, p. 343-347, 2010


Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health


Data de publicação: 2010