Chikungunya virus takes centre stage in virally induced arthritis: Possible cellular and molecular mechanisms to pathogenesis
Autor(es): Jaffar-B-jee Marie Christine, Das Trina, Hoarau Jean Jacques, Krejbich Trotot Pascale, Denizot Mélanie, Ribera Anne, Roques Pierre, Gasque Philippe
Resumo: Chikungunya virus (CHIKV) causes an acute symptomatic illness with fever, skin rash (hypersensitivity vasculitis), incapacitating arthralgia which can evolve to chronic arthritis in elderly patients. Clinical observations from cohort studies have been corroborated with data from experimental infection in several mouse - non-human primate models as discussed herein.
Imprenta: Microbes and Infection, v. 11, n. 14-15, p. 1206-1218, 2009
Identificador do objeto digital: 10.1016/j.micinf.2009.10.001
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Immunology
Data de publicação: 2009
