Autor(es): Sam I-C, AbuBakar S

Resumo: Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which causes epidemic fever, rash - polyarthralgia in Africa - Asia. Two outbreaks have been reported in Malaysia, in Klang, Selangor (1998) - Bagan Panchor, Perak (2006). It is not known if the outbreaks were caused by the recent introduction of CHIKV, or if the virus was already circulating in Malaysia. Seroprevalence studies from the 1960s suggested previous disease activity in certain parts of the country. In Asia, CHIKV is thought to be transmitted by the same mosquitoes as dengue, Aedes aegypti - Ae. albopictus. Due to similarities in clinical presentation with dengue, limited awareness, - a lack of laboratory diagnostic capability, CHIKV is probably often underdiagnosed or misdiagnosed as dengue. Treatment is supportive. The prognosis is generally good, although some patients experience chronic arthritis. With no vaccine or antiviral available, prevention - control depends on surveillance, early identification of outbreaks, - vector control. CHIKV should be borne in mind in sporadic cases, - in patients epidemiologically linked to ongoing local or international outbreaks or endemic areas.

Imprenta: The Medical Journal of Malaysia, v. 61, n. 2, p. 264-269, 2006

Descritores: Chikungunya virus - DNA ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Vaccine ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemic ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology ; Chikungunya virus - Public health

Data de publicação: 2006

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