Chikungunya fever: an epidemiological review of a re-emerging infectious disease

Autor(es): Staples J Erin, Breiman Robert F, Powers Ann M


Resumo: Chikungunya fever is an acute febrile illness associated with severe, often debilitating polyarthralgias. The disease is caused by Chikungunya virus (CHIKV), an arthropod-borne virus that is transmitted to humans primarily via the bite of an infected mosquito. Since a re-emergence of CHIKV in 2004, the virus has spread into novel locations, such as Europe, - has led to millions of cases of disease throughout countries in - around the Indian Ocean. The risk of importation of CHIKV into new areas is ever present because of the high attack rates associated with the recurring epidemics, the high levels of viremia in infected humans, - the worldwide distribution of the vectors responsible for transmitting CHIKV. In this review, we will characterize the epidemiology - global expansion of CHIKV, describe the clinical features - laboratory testing for the disease, - discuss priorities for further studies needed for effective disease control - prevention.


Imprenta: Clinical Infectious Diseases, v. 49, n. 6, p. 942-948, 2009


Identificador do Objeto Digital: 10.1086/605496


Descritores: Chikungunya virus - Biochemistry ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Molecular screening ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemic ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health


Data de Publicação: 2009