Autor(es): Schwartz Olivier, Albert Matthew L

Resumo: Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus responsible for a recent, unexpectedly severe epidemic in countries of the Indian Ocean region. Although many alphaviruses have been well studied, little was known about the biology - pathogenesis of CHIKV at the time of the 2005 outbreak. Over the past 5 years there has been a multidisciplinary effort aimed at deciphering the clinical, physiopathological, immunological - virological features of CHIKV infection. This Review highlights some of the most recent advances in our underst-ing of the biology of CHIKV - its interactions with the host.

Imprenta: Nature Reviews, Microbiology, v. 8, n. 7, p. 491-500, 2010

Identificador do objeto digital: 10.1038/nrmicro2368

Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Epidemic ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology

Data de publicação: 2010

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