Autor(es): Hollidge Bradley S, González-Scarano Francisco, Soldan Samantha S

Resumo: Arthropod-borne viruses (arboviruses) are of paramount concern as a group of pathogens at the forefront of emerging - re-emerging diseases. Although some arboviral infections are asymptomatic or present with a mild influenza-like illness, many are important human - veterinary pathogens causing serious illness ranging from rash - arthritis to encephalitis - hemorrhagic fever. Here, we discuss arboviruses from diverse families (Flaviviruses, Alphaviruses, - the Bunyaviridae) that are causative agents of encephalitis in humans. An underst-ing of the natural history of these infections as well as shared mechanisms of neuroinvasion - neurovirulence is critical to control the spread of these viruses - for the development of effective vaccines - treatment modalities.

Palavras-Chave: Arbovirus; Flavivirus; Bunyaviridae; Alphavirus; Encephalitis

Imprenta: Journal of Neuroimmune Pharmacology, v. 5, n. 3, p. 428-442, 2010

Identificador do objeto digital: 10.1007/s11481-010-9234-7

Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Neurovirulence ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Infectious diseases ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Vaccine ; Chikungunya virus - Chikungunya fever

Data de publicação: 2010

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