Antiviral perspectives for Chikungunya virus
Autor(es): Parashar Deepti, Cherian Sarah
Resumo: Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has a major health impact in humans - causes acute febrile illness in humans accompanied by joint pains -, in many cases, persistent arthralgia lasting for weeks to years. CHIKV reemerged in 2005-2006 in several parts of the Indian Ocean isl-s - India after a gap of 32 years, causing millions of cases. The re-emergence of CHIKV has also resulted in numerous outbreaks in several countries in the eastern hemisphere, with a threat to further exp- in the near future. However, there is no vaccine against CHIKV infection licensed for human use, - therapy for CHIKV infection is still mainly limited to supportive care as antiviral agents are yet in different stages of testing or development. In this review we explore the different perspectives for chikungunya treatment - the effectiveness of these treatment regimens - discuss the scope for future directions.
Imprenta: BioMed Research International, v. 2014, p. 631642, 2014
Identificador do objeto digital: 10.1155/2014/631642
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Transmission ; Chikungunya virus - Vaccine ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2014
