An outbreak of Mayaro virus disease in Belterra, Brazil I. Clinical and virological findings
Autor(es): Pinheiro F P, Freitas R B, Travassos da Rosa J F, Gabbay Y B, Mello W A, LeDuc J W
Resumo: An outbreak of human illness caused by Mayaro (MAY) virus occurred in Belterra, Pará, Brazil in the first half of 1978. A total of 55 cases were confirmed, 43 by virus isolation - serology, - 12 by serology alone. The disease in Belterra presented as a distinct clinical syndrome characterized by fever, arthralgia - exanthema. No fatalities could be attributed to MAY virus infection. Arthralgia, accompanied by joint edema in 20% of cases, was a very prominent sign which caused temporary incapacity in many patients. Arthralgia was present in virtually all confirmed cases - persisted in some for at least 2 months, although with decreasing severity. Rash was present in two-thirds of the cases, - was either maculopapular or micropapular. The incidence of rash was higher in children than in adults. Contrary to arthralgia, which started with the onset of clinical illness, rash usually appeared on the 5th day - faded within 3-4 days. Fever, chills, headache, myalgia, lymph-adenopathy - other minor clinical manifestations were also recorded, - generally persisted for from 2-5 days. Leucopenia was a constant finding in all cases. Mild albuminuria was seen in four of 25 patients, - slight thrombocytopenia was seen in 10 of 20 cases. The fact that viremia levels higher tha 5.0 log10/1.0 ml of blood were recorded in 10 patients rises the possibility that man may have be an amplifying host in the MAY virus cycle. The MAY virus illness, as seen in Belterra, has clinical features similar to those observed in persons infected with chikungunya virus.
Imprenta: The American Journal of Tropical Medicine and Hygiene, v. 30, n. 3, p. 674-681, 1981
Identificador do objeto digital: 10.4269/ajtmh.1981.30.674
Descritores: Chikungunya virus - Cytopathology ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Serology ; Chikungunya virus - Viral infections ; Chikungunya virus - Serology ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health ; Chikungunya virus - Rash maculopapular
Data de publicação: 1981
