A sero-epidemiological survey for certain arboviruses (Togaviridae) in Pakistan

Capa:A sero-epidemiological survey for certain arboviruses (Togaviridae) in Pakistan

Autor(es): Darwish M A, Hoogstraal H, Roberts T J, Ahmed I P, Omar F


Resumo: Complement-fixation test reactions to eight viruses of the family Togaviridae were studied in 372 serum samples (157 rodents, 172 domestic animals, 43 humans) from Pakistan. Antibodies to each tested virus were detected. The highest over-all prevalence rates were for West Nile (WN) (7.8%), Japanese encephalitis (JE) (3.2%) - Zika (ZIKA) (2.4%) viruses, followed by Sindbis (SIN), Chikungunya (CHIK), Ug-a S (UGS) - Royal Farm (RF) viruses (1.6 to 1.3%). One human serum (male, age 58 years) reacted with Dengue-1 (DEN) virus antigen (titre 1:32). Antibodies to each virus except RF were detected in human sera; antibodies to RF virus were detected only in rodent - domestic animal sera. The roles of rodents in the epidemiology of WN, JE - ZIKA viruses should be investigated. At least six of these eight viruses cause fevers in humans (fevers of unknown origin comprise about one third of the febrile episodes recorded in Pakistan).


Imprenta: Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 77, n. 4, p.442-445, 1983


Identificador do objeto digital: 10.1016/0035-9203(83)90106-2


Descritores: Chikungunya virus - Arbovirus ; Chikungunya virus - Flaviviridae ; Chikungunya virus - Pathogenesis ; Chikungunya virus - Proteins ; Chikungunya virus - Antibodies ; Chikungunya virus - Serology ; Chikungunya virus - Viral infections ; Chikungunya virus - Serology ; Chikungunya Virus - Virus ; Chikungunya virus - Dengue ; Chikungunya virus - Epidemiology ; Chikungunya virus - Immunology


Data de publicação: 1983