A child with serious Chikungunya virus (CHIKV) infection requiring intensive care, after an outbreak
Autor(es): Menon P Ramesh, C Krishnan, Sankar Jayaram, Gopinathan K M, Mohan Girija
Resumo: A 5 1/2-yr-old boy presented with high grade fever for 4 days, - cervical adenitis, body ache, arthralgia, followed by sudden onset of breathlessness. He had clinical, electrocardiographic - echo evidence of myocarditis - congestive cardiac failure. An enzyme-linked immunosorbent assay (MAC-IgM ELISA) with serum collected 5 days after disease onset showed IgM antibodies to CHIKV. He was managed conservatively - started showing symptomatic improvement by 3 days. At discharge, a repeat Echocardiogram (a week later) showed normal left ventricular (LV) function with mild Mitral regurgitation. On follow up, after 2 months, child remains asymptomatic. Other common aetiological agents were screened for - found negative. This may indicate a probable cardiac tropism for the virus.
Palavras-Chave: Cardiac dysfunction; Critically ill child; Viral infections
Imprenta: Indian Journal of Pediatrics, v. 77, n. 11, p. 1326-1328, 2010
Identificador do objeto digital: 10.1007/s12098-010-0174-2
Descritores: Chikungunya virus - Pathogenesis ; Chikungunya virus - Antibodies ; Chikungunya virus - Viral infections ; Chikungunya Virus - Virus ; Chikungunya virus - Chikungunya fever ; Chikungunya virus - Epidemiology ; Chikungunya virus - Public health
Data de publicação: 2010
