Current infection status and epidemic risk analysis of Dengue fever and Chikungunya in Guangdong province, from 1990 to 2012
Autor(es): Guo Runing, Peng Zhiqiang, Song Tie, He Jianfeng, Zhong Haojie, Li Linghui, Liang Wenjia
Resumo: To underst- the status of infection - epidemic trend of Dengue fever - Chikungunya in Guangdong. Retrospective survey - literature review were used to obtain data on the incidence, etiology of Dengue - Chikungunya. Serological survey was conducted to detect the specific-antibodies in healthy individuals for both Dengue virus(DENV)- Chikungunya virus (CHIKV). Three epidemics of Dengue fever were observed during 1990-2012, with the annual incidence rates as 9.75/100 000 in 1995, 1.76/100 000 in 2002 - 1.25/100 000 in 2006, respectively. The predominant epidemic strains appeared to be DENV-2 - DENV-4 during 1990-1994. Since 1995,DENV-1 had become the predominant transmission strain which lasted for almost 13 years. Co-existence of multiple serotypes of DENV started in 2009. Of the 7 718 sera from healthy population during 2003-2012, 180 specimens were detected positive for specific DENV-IgG antibody, ended with a sero-prevalence rate of 2.33%. All 2 132 sera in 2012 were detected negative for CHIKV-IgG antibody. The overall exposure level to Dengue was considered to be low in Guangdong province. However, the predominant transmission mode caused by DENV-1 had been gradually changed into the co-existence of multiple serotypes with the endemic signs appeared in some part of the areas. Chikungunya was a newly emerging disease in Guangdong since local people were lack of basic immunity barrier. Surveillance - control programs thus seemed important.
Palavras-Chave: Dengue; Chikungunya; Infection
Imprenta: Zhonghua Liu Xing Bing Xue Za Zhi, v. 35, n. 2, p. 167-169, 2014
Identificador do objeto digital: 10.3760/cma.j.issn.0254-6450.2014.02.014
Descritores: Chikungunya virus - Pathogenesis; Chikungunya virus - Proteins; Chikungunya virus - Antibodies; Chikungunya virus - Viral infections; Chikungunya Virus - Virus; Chikungunya virus - Transmission; Chikungunya virus - Chikungunya fever; Chikungunya virus - Dengue; Chikungunya virus - Epidemic; Chikungunya virus - Epidemiology; Chikungunya virus - Public health
Data de publicação: 2014
