Immunotoxicity activity from the essential oils of coriander (Coriandrum sativum) seeds
Autor(es): Chung, Ill-Min; Ahmad, Ateeque; Kim, Eun-Hye; Kim, Seung-Hyun; Jung, Woo-Suk; Kim, Jin-Hoi; Nayeem, Abdul; Nagella, Praveen
Resumo: The seeds of the Coriandrum sativum were extracted and the essential oil composition and immunotoxicity effects were studied. The analysis of the essential oil was conducted by gas chromatography ; mass spectroscopy, which revealed 33 components, representing 99.99% of the total oil from the seeds of coriander. The major components are linalool (55.09%), [alpha]-pinene (7.49%), 2,6-Octadien-1-ol, 3,7-dimethyl-, acetate, (E)-(5.70%), geraniol (4.83%), 3-Cyclohexene-1-methanol, [alpha],[alpha],4-trimethyl-(4.72%), hexadecanoic acid (2.65%), tetradecanoic acid (2.49%), 2-[alpha]-pinene (2.39%), citronellyl acetate (1.77%), and undecanal (1.29%). The seed oil had significant toxic effects against the larvae of Aedes aegypti with an LC sub(50) value of 21.55 ppm and LC sub(90) value of 38.79 ppm. The above data indicate that the major components in the essential oil of coriander play an important role as immunotoxicity on the A. aegypti.
Palavras-Chave: Aedes aegypti; Coriandrum sativum; Essential oils; Immunotoxicity effects; Linalool
Imprenta: Immunopharmacology and Immunotoxicology, v. 34, n. 3, p. 499-503, 2012.
Descritores: Aedes aegypti - Immune response ; Aedes aegypti - Immunology
Data de publicação: 2012
