Immunotoxicity activity of the major essential oil of Filipendula glaberrima against Aedes aegypti L
Autor(es): Lee, S. J.; Moon, H. I.
Resumo: The aerial parts of Filipendula glaberrima were extracted and the composition and immunotoxicity effects of major essential oils were studied. The analyses conducted by gas chromatography and mass spectroscopy (GC-MS) revealed the essential oils of F. glaberrima. The F. glaberrima essential oil (FGEO) yield was 0.046%, and GC/MS analysis revealed that its major constituents were b-famesol (2.96%), I-a-terpineol (2.43%), benzenemethanol (2.87%), (Z)-3-hexen-1-ol (5.23%), and 2,6-bis(1,1-dimethylethyl)-4-methylphenol (1.91%). The essential oil had a significant toxic effect against early fourth stage larvae of Aedes aegypti L with an LC sub(50) value of 28.43 ppm and an LC sub(90) value of 76.21 ppm. The results could be useful in search for newer, safer, and more effective natural immunotoxicity agents against A. aegypti.
Palavras-Chave: Toxicity tests; Mortality causes; Immunotoxicity; Chemical composition; Larvae; Essential oils; Immune response; Aedes aegypti; Filipendula
Imprenta: Immunopharmacology and Immunotoxicology, v. 32, n. 4, p. 617-619, 2010.
Descritores: Aedes aegypti - Immune response ; Aedes aegypti - Immunology
Data de publicação: 2010
