Superoxide dismutase in the anal gills of the mosquito larvae of Aedes aegypti : Its inhibition by alpha -terthienyl.
Autor(es): Nivsarkar, M.; Kumar, G. P.; Laloraya, M.; Laloraya, M. M.
Resumo: The anal gills of the mosquito larvae of Aedes aegypti were shown to possess superoxide dismutase (EC 1.15.1.1) activity, which increased with the maturation of the larvae from instar 1 to instar 4. This enzyme was highly inhibited upon treatment of the larvae with alpha -terthienyl (2,2':5,2"-terthiophene) and subsequent exposure to long-wave ultraviolet light. Inhibition also occurred with treatment of the crude enzyme extract in a similar fashion. Exposure of the enzyme to the ultraviolet light alone or the treatment of the enzyme with alpha -terthienyl in darkness could not manifest this inhibition. This finding adds a new dimension to the complex mechanism(s) proposed for the photodynamic toxicity of alpha -terthienyl.
Palavras-Chave: Metabolites; Photochemical reactions; Insecticides; Enzyme inhibitors; Enzymatic activity; Insect larvae; Aquatic insects; Plant extracts; Larvicides; Aedes aegypti; Asteraceae; Culicidae; Diptera
Imprenta: Archives of Insect Biochemistry and Physiology, v. 16, n. 4, p. 249-255, 1991.
Descritores: Aedes aegypti - Larvicide
Data de publicação: 1991
