Multiple insecticide resistance in Aedes aegypti (Diptera: Culicidae) populations compromises the effectiveness of dengue vector control in French Guiana
Autor(es): Dusfour, I.; Thalmensy, V.; Gaborit, P.; Issaly, J.; Carinci, R.; Girod, R.
Resumo: In French Guiana, pyrethroids and organophosphates have been used for many years against Aedes aegypti. We aimed to establish both the resistance level of Ae. aegypti and the ultra low volume spray efficacy to provide mosquito control services with practical information to implement vector control and resistance management. Resistance to deltamethrin and fenitrothion was observed. In addition, the profound loss of efficacy of AquaK' othrine registered and the moderate loss of efficacy of Paluthion registered 500 were recorded. Fenitrothion remained the most effective candidate for spatial application in French Guiana until its removal in December 2010. Further investigation of the mechanism of resistance to deltamethrin demonstrated the involvement of mixed-function oxidases and, to a lesser extent, of carboxylesterases. However, these observations alone cannot explain the level of insecticide resistance we observed during tube and cage tests.
Palavras-Chave: Insecticides; Pest control; Cages; Public health; Disease transmission; Control resistance; Dengue; Carboxylesterase; Vectors; Organophosphates; Aedes aegypti; Culicidae; Diptera
Imprenta: Memorias do Instituto Oswaldo Cruz, v. 106, n. 3, p. 346-352, 2011.
Descritores: Aedes aegypti - Transmission ; Aedes aegypti - Dengue ; Aedes aegypti - Public health
Data de publicação: 2011
